Nucleic Acid Aptamers: Selection, Characterization, and Application (Methods in Molecular Biology)

This volume provides protocol references covering recent developments in the aptamer field. Within the last decade aptamers have become more and more popular and their sophisticated biophysical properties together with their ability to be easily modified and thus adapted to various regimens makes them a very promising class of compounds. Divided into three sections the book covers selection a series of analytical methods to assess biophysical properties of aptamer-target interactions as well as various applications of aptamers. Written for the highly successful Methods in Molecular Biol ogy series chapters include introductions to their respective topics lists of the necessary materials and reagents step-by-step readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Practical and easy to follow Nucleic Acid Aptamers: Selection Characterization and Application provides a state-of-the-art summary of recent developments in the aptamer field and will be a helpful resource for scientists in the life sciences working with aptamers as tools to elucidate biological systems.